CIBN
CIBN
 
MREdictorCS
Custom Sequence MicroRNA Recognition Elements Prediction Tool

MREdictorCS is an highly accurate method for the identification of bona-fide microRNAs targets within mammalian genes.
Main improvements introduced by this method, compared to state-of-the-art algorithms, is the modeling of the microRNA-target interaction as a two step reaction of duplex nucleation at the seed level, followed by an extended pairing of the 3'-tail, and the employement of the Pumilio RNA binding proteins signature to evaluate the accessibility of targets residing within locally stable secondary structures of the target 3'-UTR.

MREdictorCS, allows to input a custom FASTA sequence to perform the prediction.
Actually only 1 sequence at a time is supported.



MREdictorCS - Query form


Subject mRNA (FASTA format): 




MRE's class:  Organism: 
Available miRNAs:



Selected miRNAs (0):


ΔGPerfect:   kcal/mol ΔGImperfect:   kcal/mol

Accessibility window:  ΔGAccess:   kcal/mol


PWM cut-off:  UPstream range:  DOWNstream range: 


Email address (optional):




Contact the webmaster
Epigenetics Unit © 2013-2014. All rights reserved.
Home