MicroRNA Recognition Elements Prediction Tool

MREdictor is an highly accurate method for the identification of bona-fide microRNAs targets within mammalian genes.
Main improvements introduced by this method, compared to state-of-the-art algorithms, is the modeling of the microRNA-target interaction as a two step reaction of duplex nucleation at the seed level, followed by an extended pairing of the 3'-tail, and the employement of the Pumilio RNA binding proteins signature to evaluate the accessibility of targets residing within locally stable secondary structures of the target 3'-UTR.

To use MREdictor, please input a valid RefSeq ID, or use the Genome Mapper tool to browse a genome and find a gene of interest. A maximum of 20 microRNAs can be used for scanning, in order to avoid server overloading.

MREdictor - Query form

Subject mRNA (RefSeq ID): 

MRE's class:  Organism: 
Available miRNAs:

Selected miRNAs (0):

ΔGPerfect:   kcal/mol ΔGImperfect:   kcal/mol

Accessibility window:  ΔGAccess:   kcal/mol

PWM cut-off:  UPstream range:  DOWNstream range: 

Email address (optional):

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